The Despair is a highly effective skill for the Blood Mage in Path of Exile 2. Based on our latest ladder analysis of 22 top players in the 90-plus bracket, this build frequently maximizes damage by utilizing support gems such as Efficiency II, Heightened Curse, Chaos Mastery. To optimize survivability and DPS, players commonly allocate key passives like Critical Overload, Sanguimancy, Vitality Siphon on the skill tree.

Despair
(Blood Mage) Builds
Sample size: 22 characters analyzed.
Last updated: 2026-07-28 19:43:54 UTC
Below data represents gem links within this cohort. Selected main skills are strictly isolated.
★ Selected Main Skills
Other Active Skills & Auras
Flasks Distribution
Main Hand (Set I)
Top Bases / Uniques
Top Explicit Mods
#% increased [Spell] Damage
54.5%
[Gain] #% of Damage as Extra [Cold] Damage
40.9%
[Gain] #% of Damage as Extra [Fire] Damage
40.9%
#% increased [Critical|Critical Hit Chance] for [Spell|Spells]
36.4%
[Gain] #% of Damage as Extra [Lightning] Damage
27.3%
#% increased [CriticalDamageBonus|Critical Spell Damage Bonus]
22.7%
# to Level of all [Fire|Fire] [Spell|Spell] Skills
18.2%
# to maximum Mana
18.2%
# to Level of all [Chaos|Chaos] [Spell|Spell] Skills
13.6%
# to Level of all [Lightning|Lightning] [Spell|Spell] Skills
13.6%
Offhand (Set I)
Top Bases / Uniques
Top Explicit Mods
# to Level of all [Cold] Skills
36.4%
# to Level of all [Fire] Skills
36.4%
# to Level of all [Lightning] Skills
36.4%
#% increased [Evasion|Evasion] Rating
36.4%
#% to [MaximumResistances|Maximum Cold Resistance]
36.4%
#% to [MaximumResistances|Maximum Fire Resistance]
36.4%
#% to [MaximumResistances|Maximum Lightning Resistance]
36.4%
#% increased [EnergyShield|Energy Shield]
22.7%
# to Level of all [Spell|Spell] Skills
13.6%
# to maximum [EnergyShield|Energy Shield]
13.6%
Helmet
Top Bases / Uniques
Top Explicit Mods
#% increased [Critical|Critical Hit] Chance
77.3%
Has no [Attributes|Attribute] Requirements
72.7%
#% increased [Evasion] and [EnergyShield|Energy Shield]
45.5%
Skill Gems have no [Attributes|Attribute] Requirements
45.5%
#% to [Resistances|Chaos Resistance]
40.9%
# to maximum Life
18.2%
#% increased [EnergyShield|Energy Shield]
18.2%
# to maximum Mana
13.6%
#% to [Resistances|Lightning Resistance]
13.6%
# to maximum [EnergyShield|Energy Shield]
9.1%
Body Armour
Top Bases / Uniques
Top Explicit Mods
#% increased [EnergyShield|Energy Shield]
81.8%
# to maximum [EnergyShield|Energy Shield]
63.6%
#% to [Resistances|Lightning Resistance]
54.5%
#% to [Resistances|Cold Resistance]
40.9%
#% to [Resistances|Fire Resistance]
40.9%
# to maximum Life
36.4%
#% increased [ESRechargeRate|Energy Shield Recharge Rate]
13.6%
#% reduced [Attributes|Attribute] Requirements
13.6%
# Life Regeneration per second
9.1%
# to Level of all [Corrupted] Skill Gems
9.1%
Gloves
Top Bases / Uniques
Top Explicit Mods
# to maximum Life
63.6%
#% increased [EnergyShield|Energy Shield]
59.1%
# to maximum [EnergyShield|Energy Shield]
36.4%
# to maximum Mana
22.7%
#% increased [CriticalDamageBonus|Critical Damage Bonus]
22.7%
# to [Dexterity|Dexterity]
18.2%
#% to [Resistances|Cold Resistance]
18.2%
# to [Intelligence|Intelligence]
13.6%
#% increased [ItemRarity|Rarity of Items] found
13.6%
#% to [Resistances|Chaos Resistance]
13.6%
Boots
Top Bases / Uniques
Top Explicit Mods
#% increased Movement Speed
95.5%
#% increased [EnergyShield|Energy Shield]
90.9%
# to [Intelligence|Intelligence]
86.4%
[Curse] Skills have #% increased Cast Speed
86.4%
[Curse|Curses] have no Activation Delay
86.4%
#% to [Resistances|Fire Resistance]
9.1%
Amulet
Top Bases / Uniques
Top Explicit Mods
# to Level of all [Spell|Spell] Skills
81.8%
# to maximum [EnergyShield|Energy Shield]
45.5%
# to [Spirit|Spirit]
36.4%
# to maximum Life
31.8%
#% increased maximum [EnergyShield|Energy Shield]
31.8%
# to maximum Mana
27.3%
#% increased [ItemRarity|Rarity of Items] found
27.3%
# to [Dexterity|Dexterity]
22.7%
# to [Strength|Strength]
22.7%
#% increased [Spell] Damage
22.7%
Ring 1
Top Bases / Uniques
Top Explicit Mods
#% increased [Spell] Damage
54.5%
#% increased Cast Speed
50%
#% increased [ItemRarity|Rarity of Items] found
45.5%
# to maximum Life
40.9%
#% to [Resistances|Chaos Resistance]
40.9%
#% increased [Critical|Critical Hit Chance] for [Spell|Spells]
36.4%
#% to all [ElementalDamage|Elemental] [Resistances]
31.8%
# to maximum Mana
27.3%
#% to [Resistances|Cold Resistance]
27.3%
#% to [Resistances|Lightning Resistance]
27.3%
Ring 2
Top Explicit Mods
# to maximum Life
45.5%
#% increased Cast Speed
40.9%
#% to [Resistances|Fire Resistance]
36.4%
#% to [Resistances|Lightning Resistance]
36.4%
#% increased [Spell] Damage
31.8%
# to maximum Mana
27.3%
#% increased [ItemRarity|Rarity of Items] found
27.3%
#% to all [ElementalDamage|Elemental] [Resistances]
27.3%
#% to [Resistances|Cold Resistance]
22.7%
Reflects opposite Ring
22.7%
Belt
Top Explicit Mods
Has # [Charm] Slots
95.5%
#% of [Flask|Flask] Recovery applied Instantly
54.5%
Legacy of [LegacyOfQuicksilver|Quicksilver]
54.5%
Legacy of [LegacyOfGold|Gold]
50%
# to maximum Life
45.5%
All [MagesLegacy|Mage's Legacies] have #% increased effect per duplicate [MagesLegacy|Mage's Legacy] you have
45.5%
Legacy of [LegacyOfBismuth|Bismuth]
36.4%
#% to [Resistances|Cold Resistance]
27.3%
#% to [Resistances|Fire Resistance]
27.3%
# to # [Physical|Physical] [Thorns|Thorns] damage
22.7%
Main Hand (Set II)
Top Explicit Mods
# to maximum Mana
54.5%
#% increased Cast Speed
45.5%
#% increased [Spell] Damage
40.9%
[Gain] #% of Damage as Extra [Fire] Damage
27.3%
#% increased Mana Regeneration Rate
22.7%
[Gain] #% of Damage as Extra [Cold] Damage
22.7%
[Gain] #% of Damage as Extra [Lightning] Damage
18.2%
# to Level of all [Spell|Spell] Skills
13.6%
# to [Intelligence|Intelligence]
13.6%
#% increased [Cold] Damage
13.6%
Interactive Meta Heatmap
No Node Selected
Key Notables & Keystones
Critical Overload
(22)100%✕ Remove
Sanguimancy
(22)100%✕ Remove
Vitality Siphon
(22)100%✕ Remove
Sunder the Flesh
(22)100%✕ Remove
Crimson Power
(22)100%✕ Remove
Grasping Wounds
(22)100%✕ Remove
Sudden Escalation
(21)95.5%✕ Remove
Heartbreaking
(21)95.5%✕ Remove
For the Jugular
(21)95.5%✕ Remove
Whispers of Doom
(20)90.9%✕ Remove
Throatseeker
(20)90.9%✕ Remove
Pure Energy
(19)86.4%✕ Remove
Deadly Force
(19)86.4%✕ Remove
Controlling Magic
(19)86.4%✕ Remove
Heartstopping
(17)77.3%✕ Remove
Patient Barrier
(17)77.3%✕ Remove
Preservation
(16)72.7%✕ Remove
Roil
(16)72.7%✕ Remove
Practiced Signs
(15)68.2%✕ Remove
True Strike
(15)68.2%✕ Remove
Careful Assassin
(14)63.6%✕ Remove
Desensitisation
(12)54.5%✕ Remove
Pure Chaos
(12)54.5%✕ Remove
Endless Blizzard
(11)50%✕ Remove
Blood Magic
(11)50%✕ Remove
Dampening Shield
(10)45.5%✕ Remove
Mind Over Matter
(10)45.5%✕ Remove
Critical Exploit
(10)45.5%✕ Remove
Shredding Force
(9)40.9%✕ Remove
Barbaric Strength
(9)40.9%✕ Remove
Reverberation
(8)36.4%✕ Remove
Invocated Efficiency
(8)36.4%✕ Remove
Lingering Whispers
(7)31.8%✕ Remove
Vulgar Methods
(7)31.8%✕ Remove
Ingenuity
(7)31.8%✕ Remove
Tides of Change
(7)31.8%✕ Remove
Deep Trance
(6)27.3%✕ Remove
Master of Hexes
(6)27.3%✕ Remove
Zone of Control
(6)27.3%✕ Remove
Melding
(5)22.7%✕ Remove
Chronomancy
(5)22.7%✕ Remove
Raw Power
(5)22.7%✕ Remove
Overzealous
(4)18.2%✕ Remove
Impending Doom
(4)18.2%✕ Remove
Efficient Inscriptions
(4)18.2%✕ Remove
Enhanced Barrier
(4)18.2%✕ Remove
Dark Entries
(4)18.2%✕ Remove
Spiral into Insanity
(3)13.6%✕ Remove
Arcane Intensity
(3)13.6%✕ Remove
Thaumaturgic Generator
(3)13.6%✕ Remove
Eldritch Battery
(3)13.6%✕ Remove
Remnant Attraction
(2)9.1%✕ Remove
Turn the Clock Forward
(2)9.1%✕ Remove
Raw Mana
(2)9.1%✕ Remove
Sanguine Tolerance
(2)9.1%✕ Remove
Rupturing Pins
(2)9.1%✕ Remove
Tempered Mind
(2)9.1%✕ Remove
Dreamcatcher
(2)9.1%✕ Remove
Mental Alacrity
(2)9.1%✕ Remove
Potent Incantation
(2)9.1%✕ Remove
Brain Freeze
(2)9.1%✕ Remove
Bone Chains
(2)9.1%✕ Remove
Turn the Clock Back
(2)9.1%✕ Remove
Invigorating Archon
(2)9.1%✕ Remove
Energising Archon
(2)9.1%✕ Remove
Brain Storm
(2)9.1%✕ Remove
Cooked
(2)9.1%✕ Remove
Chakra of Elements
(2)9.1%✕ Remove
Insightfulness
(1)4.5%✕ Remove
Illuminated Crown
(1)4.5%✕ Remove
Final Barrage
(1)4.5%✕ Remove
Void
(1)4.5%✕ Remove
Eldritch Will
(1)4.5%✕ Remove
Dependable Ward
(1)4.5%✕ Remove
Crystallised Immunities
(1)4.5%✕ Remove
Empowering Infusions
(1)4.5%✕ Remove
Right Hand of Darkness
(1)4.5%✕ Remove
Heartstopping Presence
(1)4.5%✕ Remove
Sacrificial Blood
(1)4.5%✕ Remove
Arcane Blossom
(1)4.5%✕ Remove
Power Conduction
(1)4.5%✕ Remove
Efficient Casting
(1)4.5%✕ Remove
Spell Haste
(1)4.5%✕ Remove
Savoured Blood
(1)4.5%✕ Remove
Paragon
(1)4.5%✕ Remove
Ice Storm
(1)4.5%✕ Remove
Immortal Infamy
(1)4.5%✕ Remove
Everlasting Infusions
(1)4.5%✕ Remove
Infusing Power
(1)4.5%✕ Remove
Refocus
(1)4.5%✕ Remove
Heavy Buffer
(1)4.5%✕ Remove
Shocking Limit
(1)4.5%✕ Remove
Warding Fetish
(1)4.5%✕ Remove
Spaghettification
(1)4.5%✕ Remove
Vile Mending
(1)4.5%✕ Remove
Infused Limits
(1)4.5%✕ Remove
Blood Rush
(1)4.5%✕ Remove
Empowering Remnants
(1)4.5%✕ Remove
Acceleration
(1)4.5%✕ Remove
Stormbreaker
(1)4.5%✕ Remove
Arcane Remnants
(1)4.5%✕ Remove
Spellblade
(1)4.5%✕ Remove
Frozen Limit
(1)4.5%✕ Remove
Immortal Thirst
(1)4.5%✕ Remove
Event Horizon
(1)4.5%✕ Remove
Overexposure
(1)4.5%✕ Remove
Distant Dreamer
(1)4.5%✕ Remove
Chaos Inoculation
(1)4.5%✕ Remove
Sanguimantic Rituals
(1)4.5%✕ Remove
Fated End
(1)4.5%✕ Remove
Lightning Storm
(1)4.5%✕ Remove
Infernal Limit
(1)4.5%✕ Remove
Vigorous Remnants
(1)4.5%✕ Remove
Lasting Boons
(1)4.5%✕ Remove