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Abyssal Lich
1.8%
Acolyte Of Chayula
0.9%
Amazon
0.5%
Blood Mage
3.5%
Chronomancer
0.9%
Deadeye
7.8%
Disciple Of Varashta
3%
Druid
Gemling Legionnaire
17.5%
Huntress
Infernalist
5.2%
Invoker
0.1%
Lich
1.5%
Martial Artist
24.4%
Mercenary
Monk
Oracle
5.4%
Pathfinder
1.7%
Ranger
Ritualist
1.3%
Shaman
2%
Smith Of Kitava
0.6%
Sorceress
Spirit Walker
11.3%
Stormweaver
5.1%
Tactician
1%
Titan
2.8%
Warbringer
0.3%
Warrior
Witch
Witchhunter
1.3%

Despair

(Blood Mage) Builds
<7575-8990+

Sample size: 13 characters analyzed.
Last updated: 2026-09-04 12:01:30 UTC

The Despair is a highly effective skill for the Blood Mage in Path of Exile 2. Based on our latest ladder analysis of 13 top players in the 90-plus bracket, this build frequently maximizes damage by utilizing support gems such as Efficiency II, Chaos Mastery, Heightened Curse. To optimize survivability and DPS, players commonly allocate key passives like Critical Overload, Sanguimancy, Vitality Siphon on the skill tree.

Below data represents gem links within this cohort. Selected main skills are strictly isolated.

★ Selected Main Skills

Despair
100%
└
Efficiency II
100%
└
Chaos Mastery
53.8%
└
Heightened Curse
53.8%
└
Prolonged Duration II
46.2%
└
Doedre's Undoing
46.2%
└
Impending Doom
46.2%
└
Spell Cascade
38.5%
└
Rapid Casting II
30.8%
└
Decaying Hex
23.1%
└
Burning Inscription
15.4%
└
Kalisa's Crescendo
7.7%
└
Trickster's Shard
7.7%
└
Atalui's Bloodletting
7.7%
└
Dialla's Desire
7.7%
└
Rakiata's Flow
7.7%

Other Active Skills & Auras

Life Remnants
100%
└
Harmonic Remnants II
84.6%
└
Remnant Potency I
69.2%
└
Khatal's Rejuvenation
46.2%
└
Remnant Potency III
30.8%
└
Clarity I
23.1%
└
Herbalism II
23.1%
└
Harmonic Remnants I
15.4%
└
Vitality II
7.7%
└
Cannibalism I
7.7%
Arctic Armour
84.6%
└
Freeze
100%
└
Deep Freeze
90.9%
└
Cold Mastery
81.8%
└
Knockback
72.7%
└
Blind II
9.1%
└
Cooldown Recovery II
9.1%
└
Cold Penetration
9.1%
└
Herbalism I
9.1%
└
Vitality I
9.1%
Sigil of Power
76.9%
└
Prolonged Duration II
100%
└
Magnified Area II
100%
└
Cooldown Recovery II
60%
└
Rapid Casting II
60%
└
Second Wind II
10%
└
Uhtred's Rite
10%
Convalescence
69.2%
└
Prolonged Duration II
100%
└
Cooldown Recovery II
100%
└
Rapid Casting II
88.9%
└
Second Wind II
77.8%
└
Vitality I
11.1%
└
Cannibalism I
11.1%
└
Second Wind III
11.1%
Blasphemy
61.5%
└
Slow Potency
87.5%
└
Magnified Area II
87.5%
└
Ritualistic Curse
87.5%
└
Heightened Curse
50%
Elemental Weakness
61.5%
└
Doedre's Undoing
87.5%
└
Spell Cascade
87.5%
└
Impending Doom
87.5%
└
Efficiency II
87.5%
└
Lifetap
37.5%
└
Atalui's Bloodletting
25%
└
Cold Mastery
25%
└
Magnified Area II
12.5%
└
Zarokh's Refrain
12.5%
Temporal Chains
53.8%
└
Slow Potency
100%
└
Magnified Area II
100%
└
Ritualistic Curse
100%
└
Heightened Curse
57.1%
Mana Remnants
53.8%
└
Harmonic Remnants II
100%
└
Remnant Potency I
57.1%
└
Remnant Potency III
42.9%
Parry
38.5%
Charge Regulation
23.1%
Blink
23.1%
└
Cooldown Recovery II
100%
└
Rapid Casting II
66.7%
└
Mobility
66.7%
└
Lifetap
33.3%
└
Uhtred's Constellation
33.3%
Archmage
23.1%
└
Lightning Mastery
100%
└
Clarity I
33.3%
└
Herbalism I
33.3%
└
Uhtred's Omen
33.3%
Volatile Dead
15.4%
Mana Drain
15.4%
Essence Drain
15.4%
Cast on Critical
15.4%
└
Spell Cascade
50%
└
Boundless Energy II
50%
└
Lifetap
50%
Spellslinger
15.4%
Solar Orb
15.4%
Soul Offering
7.7%
└
Minion Mastery
100%
└
Danse Macabre
100%
└
Kulemak's Dominion
100%
└
Efficiency II
100%
└
Prolonged Duration II
100%
Skeletal Cleric
7.7%
└
Amanamu's Tithe
100%
Fireball
7.7%
Galvanic Field
7.7%
Remnants of Kalguur
7.7%
└
Harmonic Remnants II
100%
└
Remnant Potency I
100%
Power Siphon
7.7%
Frostbolt
7.7%
Impurity
7.7%
└
Clarity I
100%
└
Vitality I
100%
└
Cannibalism II
100%
└
Herbalism I
100%
Lightning Bolt
7.7%
Enervating Nova
7.7%
Trinity
7.7%
└
Uhtred's Omen
100%
└
Cold Mastery
100%
Reap
7.7%
Spark
7.7%
Unearth
7.7%